GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs1056667 | 1 | rs6940053 | chr6:26562122 | HCG11 | chr6:26521934-26527610:+ | -0.22 | -4.3 | 2.03E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6940053 | chr6:26562122 | HMGN4 | chr6:26538572-26547162:+ | -0.16 | -4.19 | 3.33E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6940053 | chr6:26562122 | LOC100270746 | chr6:26987146-26988085:- | -0.14 | -3.47 | 0.000578 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6940053 | chr6:26562122 | ZNF322A | chr6:26634612-26659963:- | -0.16 | -4.64 | 4.57E-6 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6940188 | chr6:26562029 | BTN2A3 | chr6:26422317-26431927:+ | 0.18 | 4.29 | 2.16E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6940188 | chr6:26562029 | HCG11 | chr6:26521934-26527610:+ | -0.22 | -4.3 | 2.1E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6940188 | chr6:26562029 | HMGN4 | chr6:26538572-26547162:+ | -0.16 | -4.19 | 3.36E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6940188 | chr6:26562029 | LOC100270746 | chr6:26987146-26988085:- | -0.14 | -3.47 | 0.000571 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6940188 | chr6:26562029 | ZNF322A | chr6:26634612-26659963:- | -0.16 | -4.64 | 4.48E-6 | Educational attainment |
| THCA | cis | rs943466 | 1 | rs6940353 | chr6:33752550 | LEMD2 | chr6:33738991-33756906:- | 0.25 | 4.99 | 8.5E-7 | Body mass index |
| THCA | cis | rs1577917 | 1 | rs6940458 | chr6:86644992 | SNHG5 | chr6:86386726-86388451:- | -0.48 | -10.71 | 3.96E-24 | Response to antipsychotic treatment |
| THCA | cis | rs7762018 | 1 | rs6941766 | chr6:170131653 | C6orf70 | chr6:170151721-170181617:+ | 0.25 | 5.11 | 4.56E-7 | Thiazide-induced adverse metabolic effects in hypertensive patients |
| THCA | cis | rs7762018 | 1 | rs6941766 | chr6:170131653 | WDR27 | chr6:169857307-170102159:- | -0.18 | -5.54 | 5.0E-8 | Thiazide-induced adverse metabolic effects in hypertensive patients |
| THCA | cis | rs9322817 | 1 | rs6942231 | chr6:105191814 | HACE1 | chr6:105175968-105307794:- | -0.16 | -4.09 | 5.17E-5 | Thyroid stimulating hormone |
| THCA | cis | rs7762018 | 1 | rs6942332 | chr6:170131934 | C6orf70 | chr6:170151721-170181617:+ | 0.25 | 5.05 | 6.2E-7 | Thiazide-induced adverse metabolic effects in hypertensive patients |